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Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character. The tissue specific subtypes are: ⁕Slow-twitch skeletal muscle isoform troponin I, TNNI1 ⁕Fast-twitch skeletal muscle isoform troponin I, TNNI2 ⁕Cardiac troponin I, TNNI3

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tropological, tropologically, tropologize, tropology, tropometer, tropopause, tropophil, tropophilous, tropophyte, tropophytic

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