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- In molecular biology, platelet-derived growth factor is one of the numerous growth factors, or proteins that regulate cell growth and division. In particular, it plays a significant role in blood vessel formation, the growth of blood vessels from already-existing blood vessel tissue. Uncontrolled angiogenesis is a characteristic of cancer. In chemical terms, platelet-derived growth factor is dimeric glycoprotein composed of two A or two B chains or a combination of the two. PDGF is a potent mitogen for cells of mesenchymal origin, including smooth muscle cells and glial cells. In both mouse and human, the PDGF signalling network consists of four ligands, PDGFA-D, and two receptors, PDGFRalpha and PDGFRbeta. All PDGFs function as secreted, disulphide-linked homodimers, but only PDGFA and B can form functional heterodimers. Though it is synthesized stored and released by platelets upon activation, it is produced by a plethora of cells including smooth muscle cells, activated macrophages, and endothelial cells
We couldn't find any anagrams for the word platelet-derived growth factor.
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plateholder, plateiasmus, platelayer, plateless, platelet, platelike, platemaker, platemaking, plateman, platen
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"platelet-derived growth factor." Anagrams.net. STANDS4 LLC, 2024. Web. 25 May 2024. <https://www.anagrams.net/platelet-derived%20growth%20factor>.
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