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- A Mannich base is a beta-amino-ketone, which is formed in the reaction of an amine, formaldehyde (or an aldehyde) and a carbon acid. The Mannich base is an endproduct in the Mannich reaction, which is nucleophilic addition reaction of a non-enolizable aldehyde and any primary or secondary amine to produce resonance stabilized imine (iminium ion or imine salt). The addition of a carbanion from a CH acidic compound (any enolizable carbonyl compound, amide, carbamate, hydantoin or urea) to the imine gives the Mannich base.
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mannerly, manners, mannersome, manness, mannheimar, mannide, mannie, manniferous, mannify, mannikinism
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"mannich bases." Anagrams.net. STANDS4 LLC, 2024. Web. 15 May 2024. <https://www.anagrams.net/mannich%20bases>.
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