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Goserelin acetate is an injectable gonadotropin releasing hormone superagonist, also known as a luteinizing hormone releasing hormone agonist. Structurally, it is a decapeptide. Goserelin acetate is used to suppress production of the sex hormones, particularly in the treatment of breast and prostate cancer. Goserelin acetate stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile manner. This causes the disruption of the endogenous hormonal feedback systems, resulting in the down-regulation of testosterone and estrogen production. Zoladex was approved by the U.S. Food and Drug Administration in 1989 for treatment of prostate cancer.

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gortonite, gory, gos, gosain, goschen, gosh, goshawk, goshen, goshenite, goslarite

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