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Germinal centers are sites within secondary lymphoid organs where mature B lymphocytes proliferate, differentiate, mutate their antibodies, and switch the class of their antibodies during a normal immune response to an infection. During this process of rapid division and selection, B cells are known as centroblasts, and once they have stopped proliferating they are known as centrocytes. Germinal centers are an important part of the B-cell humoral immune response. They develop dynamically after the activation of B-cells by T-dependent antigen. Histologically, the GCs describe microscopically distinguishable parts in lymphoid tissues.

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germin, germina, germinability, germinable, germinal, germinally, germinance, germinancy, germinant, germinate

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"germinal center." Anagrams.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.anagrams.net/germinal%20center>.

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