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A replica technique in which cells are frozen to a very low temperature and cracked with a knife blade to expose the interior surfaces of the cells or cell membranes. The cracked cell surfaces are then freeze-dried to expose their constituents. The surfaces are now ready for shadowing to be viewed using an electron microscope. This method differs from freeze-fracturing in that no cryoprotectant is used and, thus, allows for the sublimation of water during the freeze-drying process to etch the surfaces.

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freewheeling, freewill, freewoman, freezable, freeze, freezer, freezing, freezingly, fregata, fregatae

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"freeze etching." Anagrams.net. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.anagrams.net/freeze%20etching>.

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