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CD14 (cluster of differentiation 14) is a human protein made mostly by macrophages as part of the innate immune system. It helps to detect bacteria in the body by binding lipopolysaccharide (LPS), a pathogen-associated molecular pattern (PAMP). CD14 exists in two forms, one anchored to the membrane by a glycosylphosphatidylinositol (GPI) tail (mCD14), the other a soluble form (sCD14). Soluble CD14 either appears after shedding of mCD14 (48 kDa) or is directly secreted from intracellular vesicles (56 kDa).The x-ray crystal structure of human CD14 reveals a monomeric, bent solenoid structure containing a hydrophobic amino-terminal pocket.CD14 was the first described pattern recognition receptor.

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cayuse, cayuvava, caza, cazimi, ccoya, ceanothus, cearin, cease, ceaseless, ceaselessly

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"cd14." Anagrams.net. STANDS4 LLC, 2024. Web. 21 May 2024. <https://www.anagrams.net/cd14>.

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