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- Endomorphins are considered to be natural opioid neurotransmitters central to pain relief. The two known endomorphins, endomorphin-1 and endomorphin-2, are tetrapeptides, consisting of Tyr-Pro-Trp-Phe and Tyr-Pro-Phe-Phe amino acid sequences respectively. These sequences fold into tertiary structures with high specificity and affinity for the μ-opioid receptor, binding it exclusively and strongly. Bound μ-opioid receptors typically induce inhibitory effects on neuronal activity. Endomorphin-like immunoreactivity exists within the central and peripheral nervous systems, where endomorphin-1 appears to be concentrated in the brain and upper brainstem, and endomorphin-2 in the spinal cord and lower brainstem. Because endomorphins activate the μ-opioid receptor, which is the target receptor of morphine and its derivatives, endomorphins possess significant potential as analgesics with reduced side effects and risk of addiction.
We couldn't find any anagrams for the word Endomorphins.
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endomitosis, endomitotic, endomixis, endomorph, endomorphic, endomorphism, endomorphy, endomyces, endomycetaceae, endomysial
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"Endomorphins." Anagrams.net. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.anagrams.net/Endomorphins>.
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