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A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian cells AIF is released in response to pro-apoptotic protein members of the bcl-2 protein family. It translocates to the CELL NUCLEUS and binds DNA to stimulate CASPASE-independent CHROMATIN condensation.

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We couldn't find any anagrams for the word Apoptosis Inducing Factor.

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apoplectically, apoplectiform, apoplectoid, apoplex, apoplexy, apopyle, apoquinamine, apoquinine, aporetic, aporetical

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