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A family of intracellular signaling adaptor proteins that contain caspase activation and recruitment domains. Proteins that contain this domain play a role in APOPTOSIS-related signal transduction by associating with other CARD domain-containing members and in activating INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.

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carcinosarcomata, carcinoscorpius, carcinosis, carcoon, card, cardaissin, cardamine, cardamom, cardanic, cardboard

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