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- Transforming proteins encoded by erbA oncogenes from the avian erythroblastosis virus. They are truncated versions of c-erbA, the thyroid hormone receptor (RECEPTORS, THYROID HORMONE) that have retained both the DNA-binding and hormone-binding domains. Mutations in the hormone-binding domains abolish the transcriptional activation function. v-erbA acts as a dominant repressor of c-erbA, inducing transformation by disinhibiting proliferation.
We couldn't find any anagrams for the word oncogene proteins v-erba.
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onchocerciasis, onchocercosis, oncia, oncidium, oncin, oncograph, oncography, oncologic, oncological, oncology
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